TRT was founded by four scientists and is based on
inventions resulting from their research. Dr Ana Schor and her late husband,
Professor Seth Schor, identified and cloned Migration
Stimulating Factor (MSF: a unique, highly potent, regulator of biological
processes required for normal wound healing) and discovered a three-amino-acid
peptide (IGD peptide) of MSF, which displays all of its biological activities.
Dr David Norman, an expert in biological structure determination, elucidated
the structure of IGD and with Dr Rudi Marquez, used that information to rationally
design small-organic mimetics of IGD. Dr Rudi Marquez synthesised a number of candidate mimetics including our lead compound,
TRT-8174. Drs Schor, Norman and Marquez
are the current directors of TRT.
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